Psilocybin: evidence and risks
General information, not a treatment plan. Discuss health decisions with a qualified healthcare professional.
Sources checked September 5, 2026. This page has not received independent clinical review.
Risks and urgent help
Psilocybin can cause panic, confusion and impaired judgment. Mental-health conditions, heart conditions, other drugs and medications can affect risk. Do not drive while impaired. Keep substances away from children and pets.
Do not stop or change prescribed medication without your prescriber. Avoid mixing substances; consult a healthcare professional about interactions.
Call 911 immediately if someone is unconscious, has trouble breathing or is having a seizure. For suspected poisoning, contact a poison centre promptly.
Dosing uncertainty
Mushroom potency and individual responses vary. Body weight and prior experience cannot establish a safe dose. We do not provide a dosing calculator or personalized recommendations.
NCCIH: what the evidence showsResearch is not a treatment guarantee
Health Canada reports no approved psilocybin therapeutic products in Canada. Clinical research does not establish that unsupervised use, microdosing schedules or supplement combinations are safe or effective.
CAMH: psychedelics questions and answersLegal status
Possession, production and sale are illegal in Canada unless federally authorized. An age check or website disclaimer does not provide authorization.
Health Canada: authorized access